A Novel Dual Antibody Staining Assay to Measure Estrogen Receptor Transcriptional Activity
نویسندگان
چکیده
منابع مشابه
Prothymosin alpha selectively enhances estrogen receptor transcriptional activity by interacting with a repressor of estrogen receptor activity.
We find that prothymosin alpha (PTalpha) selectively enhances transcriptional activation by the estrogen receptor (ER) but not transcriptional activity of other nuclear hormone receptors. This selectivity for ER is explained by PTalpha interaction not with ER, but with a 37-kDa protein denoted REA, for repressor of estrogen receptor activity, a protein that we have previously shown binds to ER,...
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ژورنال
عنوان ژورنال: Journal of Fluorescence
سال: 2020
ISSN: 1053-0509,1573-4994
DOI: 10.1007/s10895-020-02635-7